Structure of PDB 3o34 Chain A Binding Site BS01
Receptor Information
>3o34 Chain A (length=177) Species:
9606
(Homo sapiens) [
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EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSK
PEVEYDCDAPSHKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVP
LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEF
NEPDSEVANAGIKLENYFEELLKNLYP
Ligand information
>3o34 Chain B (length=12) Species:
9606
(Homo sapiens) [
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TKAARKSAPATY
Receptor-Ligand Complex Structure
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PDB
3o34
TRIM24 links a non-canonical histone signature to breast cancer.
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
F924 V928 E978 F979 N980 E981
Binding residue
(residue number reindexed from 1)
F95 V99 E149 F150 N151 E152
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:3o34
,
PDBe:3o34
,
PDBj:3o34
PDBsum
3o34
PubMed
21164480
UniProt
O15164
|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)
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