Structure of PDB 3o1o Chain A Binding Site BS01
Receptor Information
>3o1o Chain A (length=201) Species:
83333
(Escherichia coli K-12) [
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PLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTN
CGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQ
PDACLINRYAPGAKLCLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRND
PLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAG
K
Ligand information
>3o1o Chain B (length=12) [
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aggtaauaccgt
Receptor-Ligand Complex Structure
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PDB
3o1o
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase
Resolution
1.92 Å
Binding residue
(original residue number in PDB)
T51 P52 G53 Y55 W69 Y76 K127 L128 C129 H131
Binding residue
(residue number reindexed from 1)
T38 P39 G40 Y42 W56 Y63 K114 L115 C116 H118
Enzymatic activity
Enzyme Commision number
1.14.11.33
: DNA oxidative demethylase.
Gene Ontology
Molecular Function
GO:0005515
protein binding
GO:0008198
ferrous iron binding
GO:0035515
oxidative RNA demethylase activity
GO:0035516
broad specificity oxidative DNA demethylase activity
GO:0046872
metal ion binding
GO:0051213
dioxygenase activity
Biological Process
GO:0006281
DNA repair
GO:0006307
DNA alkylation repair
GO:0035513
oxidative RNA demethylation
GO:0042245
RNA repair
GO:0070989
oxidative demethylation
GO:0072702
response to methyl methanesulfonate
Cellular Component
GO:0005737
cytoplasm
GO:0005829
cytosol
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:3o1o
,
PDBe:3o1o
,
PDBj:3o1o
PDBsum
3o1o
PubMed
21068844
UniProt
P05050
|ALKB_ECOLI Alpha-ketoglutarate-dependent dioxygenase AlkB (Gene Name=alkB)
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