Structure of PDB 3nii Chain A Binding Site BS01

Receptor Information
>3nii Chain A (length=79) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCT
DICTEFTSGICDCGDEEAWNSPLHCKAEE
Ligand information
Receptor-Ligand Complex Structure
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PDB3nii Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases
Resolution2.1 Å
Binding residue
(original residue number in PDB)		T144 C145 V146 S172 G173 I174 D176
Binding residue
(residue number reindexed from 1)		T30 C31 V32 S58 G59 I60 D62
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:3nii, PDBe:3nii, PDBj:3nii
PDBsum3nii
PubMed20835240
UniProtP19812|UBR1_YEAST E3 ubiquitin-protein ligase UBR1 (Gene Name=UBR1)

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