Structure of PDB 3ngf Chain A Binding Site BS01

Receptor Information
>3ngf Chain A (length=258) Species: 359391 (Brucella abortus 2308) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPRFAANLSTMFNEVPFLERFRLAAEAGFGGVEFLFPYDFDADVIARELK
QHNLTQVLFNMPPGDWAAGERGMAAISGREQEFRDNVDIALHYALALDCR
TLHAMSGITEGLDRKACEETFIENFRYAADKLAPHGITVLVEPLNTRNMP
GYFIVHQLEAVGLVKRVNRPNVAVQLDLYHAQIMDGDLTRLIEKMNGAFS
HVQIASVPDRHEPDEGELNYPYLFSVLESVGYRGWVGCEYNPRGKTESGL
AWFAPYRD
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3ngf Chain A Residue 262 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ngf Crystal structure of AP endonuclease, family 2 from Brucella melitensis
Resolution1.8 Å
Binding residue
(original residue number in PDB)		E142 D177 H180 Q203 E239
Binding residue
(residue number reindexed from 1)		E142 D177 H180 Q203 E239
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.22: hydroxypyruvate isomerase.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0008903 hydroxypyruvate isomerase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3ngf, PDBe:3ngf, PDBj:3ngf
PDBsum3ngf
PubMed
UniProtQ2YLA2

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