Structure of PDB 3nfk Chain A Binding Site BS01
Receptor Information
>3nfk Chain A (length=92) Species:
9606
(Homo sapiens) [
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DNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNE
GDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRPN
Ligand information
>3nfk Chain C (length=13) Species:
11292
(Lyssavirus rabies) [
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SWESHKSGGETRL
Receptor-Ligand Complex Structure
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PDB
3nfk
Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death.
Resolution
1.43 Å
Binding residue
(original residue number in PDB)
R527 F528 G529 F530 N531 V532 K533 Q538 S545 H579 D580 V583 L584 K587
Binding residue
(residue number reindexed from 1)
R15 F16 G17 F18 N19 V20 K21 Q26 S33 H67 D68 V71 L72 K75
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:3nfk
,
PDBe:3nfk
,
PDBj:3nfk
PDBsum
3nfk
PubMed
22000519
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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