Structure of PDB 3n9p Chain A Binding Site BS01

Receptor Information

>3n9p Chain A (length=487) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PKESDRCGGCGKFTHEDKKNDFQWIGCDSCQTWYHFLCSGLEQFEYYLYE
KFFCPKCVPHTGHSIRYKVVAPHRYRWYSPNEKHLGIEVGSKTWIEDFIT
RENTVPSPTDDEVCIVEDGYEFRREFEKLGGADNWGKVFMVKDMDGLNMT
MPKPGFDLEDVVKIMGSDYEVDTIDVYNQSTYSMKLDTFRKLFRDTKNRP
LLYNFLSLEFSDNNEMKEIAKPPRFVQEISMVNRLWPDVSGAEYIKLLQR
EEYLPEDQRPKVEQFCLAGMAGSYTDFHVDFGGSSVYYHILKGEKIFYIA
APTEQNFAAYQAHETSPDTTTWFGDIANGAVKRVVIKEGQTLLIPAGWIH
AVLTPVDSLVFGGNFLHLGNLEMQMRVYHLENAIRKEIRSEEKFYFPNFE
LLHWMYMRNVLLEKITEANQEGSDMREQEKNIWTASQIMKAEMERWMDRE
LRLGPEKNAILPTDDKNKIMISVRKQIEIQTKIQNAK

Ligand information

>3n9p Chain B (length=6) Species: 6239 (Caenorhabditis elegans) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ARTKQT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3n9p Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Resolution	2.388 Å
Binding residue (original residue number in PDB)	D196 F239 Q240 W241 G243 C244 D245 Q248 W250 Y266
Binding residue (residue number reindexed from 1)	D5 F22 Q23 W24 G26 C27 D28 Q31 W33 Y49

Enzymatic activity

Enzyme Commision number

1.14.11.-

External links

PDB	RCSB:3n9p, PDBe:3n9p, PDBj:3n9p
PDBsum	3n9p
PubMed	20567261
UniProt	Q9GYI0\|KDM7_CAEEL Lysine-specific demethylase 7 homolog (Gene Name=jmjd-1.2)

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