Structure of PDB 3mxy Chain A Binding Site BS01
Receptor Information
>3mxy Chain A (length=101) Species:
9606
(Homo sapiens) [
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GSHMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKF
GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
E
Ligand information
>3mxy Chain L (length=7) Species:
9606
(Homo sapiens) [
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GYVNPTY
Receptor-Ligand Complex Structure
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PDB
3mxy
Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
R67 R86 S96 H107 F108 K109 L120 W121
Binding residue
(residue number reindexed from 1)
R16 R35 S45 H56 F57 K58 L69 W70
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3mxy
,
PDBe:3mxy
,
PDBj:3mxy
PDBsum
3mxy
PubMed
22001015
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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