Structure of PDB 3mxc Chain A Binding Site BS01
Receptor Information
>3mxc Chain A (length=98) Species:
9606
(Homo sapiens) [
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MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
Ligand information
>3mxc Chain L (length=7) Species:
9606
(Homo sapiens) [
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GYENPTY
Receptor-Ligand Complex Structure
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PDB
3mxc
Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
R67 R86 S90 S96 Q106 H107 F108 K109 L120 W121
Binding residue
(residue number reindexed from 1)
R13 R32 S36 S42 Q52 H53 F54 K55 L66 W67
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3mxc
,
PDBe:3mxc
,
PDBj:3mxc
PDBsum
3mxc
PubMed
22001015
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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