Structure of PDB 3mrj Chain A Binding Site BS01

Receptor Information
>3mrj Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>3mrj Chain P (length=9) Species: 421877 (Hepatitis C virus isolate HC-J1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CINGMCWTV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mrj Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide V5M variant
Resolution1.87 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 H70 T73 D77 Y84 Y99 T143 K146 W147 V152 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 H70 T73 D77 Y84 Y99 T143 K146 W147 V152 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3mrj, PDBe:3mrj, PDBj:3mrj
PDBsum3mrj
PubMed
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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