Structure of PDB 3mrh Chain A Binding Site BS01

Receptor Information
>3mrh Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW
Ligand information
>3mrh Chain P (length=9) Species: 421877 (Hepatitis C virus isolate HC-J1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CISGVCWTV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3mrh Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		M5 Y7 E63 K66 H70 D77 Y84 Y99 Y116 T143 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		M5 Y7 E63 K66 H70 D77 Y84 Y99 Y116 T143 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3mrh, PDBe:3mrh, PDBj:3mrh
PDBsum3mrh
PubMed25392532
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

[Back to BioLiP]