Structure of PDB 3mno Chain A Binding Site BS01

Receptor Information

>3mno Chain A (length=255) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MVPAALPQLTPTLVSLLEVIEPEVLYAGSVPDSAWRIMTTLNMLGGRQVI
AAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMVFALGWRSYRQASGNLLC
FAPDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLL
SSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLL
DSMHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKL
LFHQK

Ligand information

>3mno Chain B (length=10) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ENALLRYLLD

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3mno Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.
Resolution	1.55 Å
Binding residue (original residue number in PDB)	K585 M599 Q603 E757 E761 N765
Binding residue (residue number reindexed from 1)	K57 M71 Q75 E229 E233 N237

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:3mno, PDBe:3mno, PDBj:3mno
PDBsum	3mno
PubMed	20850457
UniProt	P06537\|GCR_MOUSE Glucocorticoid receptor (Gene Name=Nr3c1)

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