Structure of PDB 3mn8 Chain A Binding Site BS01

Receptor Information

>3mn8 Chain A (length=383) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KEDESFLQQPHYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLAL
QISRNTRSRNLLTPPVKYIANMHGDETVGRQLLVYMAQYLLGNHERISDL
GQLVNSTDIYLVPTMNPDGYALSQEGNCESLPNYVGRGNAANIDLNRDFP
DRLEAQSRQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNEC
CEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCNDSFSGGITNGAHWYELS
GGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAH
IGIKGLVTDASGFPIADANVYVAGLEEKPMRTSKRGEYWRLLTPGLYSVH
ASAFGYQTSAPQQVRVTNDNQEALRLDFKLAPV

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

3mn8 Chain A Residue 999 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3mn8 Structure-Function Analysis of the Short Splicing Variant Carboxypeptidase Encoded by Drosophila melanogaster silver.
Resolution	2.7 Å
Binding residue (original residue number in PDB)	H101 E104 H217
Binding residue (residue number reindexed from 1)	H73 E76 H181
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.4.17.22: metallocarboxypeptidase D.

Gene Ontology

	Molecular Function
GO:0004181	metallocarboxypeptidase activity
GO:0008270	zinc ion binding

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:3mn8, PDBe:3mn8, PDBj:3mn8
PDBsum	3mn8
PubMed	20600119
UniProt	P42787\|CBPD_DROME Carboxypeptidase D (Gene Name=svr)

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