Structure of PDB 3mn6 Chain A Binding Site BS01

Receptor Information
>3mn6 Chain A (length=360) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRDSYVGDEAQSKRGIL
TLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKAN
REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPI
YEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEK
LCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPS
FLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQK
EITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDES
GPSIVHRKCF
Ligand information
>3mn6 Chain X (length=19) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB3mn6 Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		G23 D24 D25
Binding residue
(residue number reindexed from 1)		G19 D20 D21
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000281 mitotic cytokinesis
GO:0006338 chromatin remodeling
GO:0007291 sperm individualization
GO:0030723 ovarian fusome organization
GO:0032507 maintenance of protein location in cell
GO:0035148 tube formation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0031011 Ino80 complex
GO:0035060 brahma complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3mn6, PDBe:3mn6, PDBj:3mn6
PDBsum3mn6
PubMed20538977
UniProtP10987|ACT1_DROME Actin-5C (Gene Name=Act5C)

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