Structure of PDB 3mlp Chain A Binding Site BS01

Receptor Information
>3mlp Chain A (length=337) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIE
RTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMT
KQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDR
FFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVH
NNSKHGRRARRLDPSEAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQ
VIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRF
IYTEPTIDYGFQRLQKVPKEVILKRAADLVEALYGMP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mlp Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Resolution2.8 Å
Binding residue
(original residue number in PDB)
R63 N66 F67 H157 C161 S162 R163 N172 G203 N204 R206 S238 K239 R242
Binding residue
(residue number reindexed from 1)
R28 N31 F32 H122 C126 S127 R128 N137 G168 N169 R171 S203 K204 R207
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:3mlp, PDBe:3mlp, PDBj:3mlp
PDBsum3mlp
PubMed20876732
UniProtQ07802|COE1_MOUSE Transcription factor COE1 (Gene Name=Ebf1)

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