Structure of PDB 3mev Chain A Binding Site BS01

Receptor Information
>3mev Chain A (length=175) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVARPGDKVA
ARVKAVDGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRVIPL
PQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHAPPQRPQDDYSVL
FEDTSYADGYSPPLNVAQRYVVACK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mev Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Resolution1.83 Å
Binding residue
(original residue number in PDB)
D194 D196 Y238 T241 T242 C243 Y245 E265 D266
Binding residue
(residue number reindexed from 1)
D81 D83 Y125 T128 T129 C130 Y132 E152 D153
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3mev, PDBe:3mev, PDBj:3mev
PDBsum3mev
PubMed21685874
UniProtQ96ES7|SGF29_HUMAN SAGA-associated factor 29 (Gene Name=SGF29)

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