Structure of PDB 3met Chain A Binding Site BS01

Receptor Information
>3met Chain A (length=174) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVARPGDKVA
ARVKAVDGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRVIPL
PQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHAPPQRPQDDYSVL
FEDTSYADGYSPPLNVAQRYVVAC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3met Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
R116 D194 D196 Y238 Q240 T241 T242 Y245 D266
Binding residue
(residue number reindexed from 1)
R3 D81 D83 Y125 Q127 T128 T129 Y132 D153
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

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Cellular Component
External links
PDB RCSB:3met, PDBe:3met, PDBj:3met
PDBsum3met
PubMed21685874
UniProtQ96ES7|SGF29_HUMAN SAGA-associated factor 29 (Gene Name=SGF29)

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