Structure of PDB 3mco Chain A Binding Site BS01

Receptor Information
>3mco Chain A (length=397) Species: 376619 (Francisella tularensis subsp. holarctica LVS) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVQYIIGIGTNSGFTIENIHLAITALESQQNIRIIRKASLYSSKAVLKAP
KEWDIRFLNTAVKISSSLKPDELLVLLKDIELKIGRDLNAPAWSPRVIDL
DILAAEDLILETDKLTIPHKELINRSFALAPLLELSKGWHHPKYVEWDLN
IRLKELGEIVKLKQTLANTIRMGIVNLSNQSFSDGNFDDNQRKLNLDELI
QSGAEIIDIGAESTKPDPISIEEEFNKLNEFLEYFKSQLANLIYKPLVSI
DTRKLEVMQKILAKHHDIIWMINDVECNNIEQKAQLIAKYNKKYVIIHNV
CDYIEQKKQILLKHGIAQQNIYFDIGFGFGDTARYLLENIIEIKRRLELK
ALVGHSRKPSVLGLTKDSNLATLDRATRELSRKLEKLDIDIIRVHKI
Ligand information
Ligand IDPH2
InChIInChI=1S/C7H9N5O2/c8-7-11-5-4(6(14)12-7)10-3(2-13)1-9-5/h13H,1-2H2,(H4,8,9,11,12,14)
InChIKeyCQQNNQTXUGLUEV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341NC1=NC2=C(N=C(CO)CN2)C(=O)N1
ACDLabs 10.04O=C1NC(=NC=2NCC(=NC1=2)CO)N
OpenEye OEToolkits 1.5.0C1C(=NC2=C(N1)N=C(NC2=O)N)CO
FormulaC7 H9 N5 O2
Name2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE
ChEMBLCHEMBL1233322
DrugBankDB02119
ZINC
PDB chain3mco Chain A Residue 423 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mco Crystal structure of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.dihydropteroate synthase bifunctional enzyme from Francisella tularensis.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		S43 V46 F59 N61 W95 F129
Binding residue
(residue number reindexed from 1)		S43 V46 F57 N59 W93 F127
Annotation score5
Gene Ontology
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UnboundLocalError		Python 3.6.8: /usr/bin/python3
Sun Nov 24 14:49:57 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '3mco', asym_id = 'A', bs = 'BS01', title = 'Crystal structure of the 6-hydroxymethyl-7,8-dih...bifunctional enzyme from Francisella tularensis. '
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='3mco', asym_id='A', bs='BS01', title='Crystal structure of the 6-hydroxymethyl-7,8-dih...bifunctional enzyme from Francisella tularensis. ')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0003848,0004156,0009396,0042558,0044237', uniprot = '', pdbid = '3mco', asym_id = 'A'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003848,0004156,0009396,0042558,0044237', uniprot='', pdbid='3mco', asym_id='A')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>