Structure of PDB 3maq Chain A Binding Site BS01

Receptor Information
>3maq Chain A (length=776) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHMAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPAD
QVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLRE
GGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRP
PLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYV
ASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGR
DNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQ
ELLGEGDRMDEIDRRFAEDKPALATYNLKNCELVTQIFHKTEIMPFLLER
ATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVM
DSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFL
DAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGT
TACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKG
AHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPT
IRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLR
IFRNEPYQEYVRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRA
ARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTR
QLQPVAEGILPFIEDNFATLMTGQLF
Ligand information
Receptor-Ligand Complex Structure
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PDB3maq Structural insight into translesion synthesis by DNA Pol II
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H258 G259 F260 F266 R365 G368 S369 V370 S399 G401 A498 G501 T505 A507 I606 R607 K614 R616 N698 V699
Binding residue
(residue number reindexed from 1)		H260 G261 F262 F268 R360 G363 S364 V365 S394 G396 A493 G496 T500 A502 I601 R602 K609 R611 N693 V694
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008296 3'-5'-DNA exonuclease activity
Biological Process
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0045004 DNA replication proofreading
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3maq, PDBe:3maq, PDBj:3maq
PDBsum3maq
PubMed20064374
UniProtP21189|DPO2_ECOLI DNA polymerase II (Gene Name=polB)

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