Structure of PDB 3m94 Chain A Binding Site BS01

Receptor Information
>3m94 Chain A (length=180) Species: 6253 (Ascaris suum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRHPLQCHWALWYLKADRSKDWEDCLKQVAVFDTVEDFWSLYNHIQAASG
LTWGSDYYLFKEGIKPMWEDENNVKGGRWLVVVDKQKRAQLLDHYWLELL
MAIIGEQFEDNGEYICGAVVNVRQKGDKVSLWTRDSLKDDVNLRIGQILK
AKLEIPDTEPIRYEVHKTGSMVKPRIVIPS
Ligand information
Receptor-Ligand Complex Structure
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PDB3m94 Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation.
Resolution2.05 Å
Binding residue
(original residue number in PDB)
H50 P51 Q53 V82 W86 N90 E145 M148 G152 E153 Q154 D157
Binding residue
(residue number reindexed from 1)
H3 P4 Q6 V35 W39 N43 E98 M101 G105 E106 Q107 D110
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3m94, PDBe:3m94, PDBj:3m94
PDBsum3m94
PubMed21965542
UniProtQ6PKX2

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