Structure of PDB 3m7n Chain A Binding Site BS01

Receptor Information
>3m7n Chain A (length=179) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRFVMPGDRIGSAEEYVKGEGVYEEGGELFAAVAGKLIIKDRVAKVESIS
PIPEIVKGDVVLGRVVDLRNSIALIEVSSKKGENRGPSNRGIGILHVSNV
DEGYVKEISEAVGYLDILKARVIGDNLRLSTKEEEMGVLRALCSNCKTEM
VREGDILKCPECGRVEKRKISTDYGKGEW
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3m7n Chain A Residue 180 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3m7n Quantitative analysis of processive RNA degradation by the archaeal RNA exosome
Resolution2.4 Å
Binding residue
(original residue number in PDB)
C143 C146 C159 C162
Binding residue
(residue number reindexed from 1)
C143 C146 C159 C162
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006401 RNA catabolic process
Cellular Component
GO:0000178 exosome (RNase complex)
GO:0005737 cytoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3m7n, PDBe:3m7n, PDBj:3m7n
PDBsum3m7n
PubMed20392821
UniProtO30033|CSL4_ARCFU Exosome complex component Csl4 (Gene Name=csl4)

[Back to BioLiP]