Structure of PDB 3lv0 Chain A Binding Site BS01

Receptor Information

>3lv0 Chain A (length=258) Species: 38323 (Bartonella henselae)

SAVMNVMVQAAMKAGRSLVRDYGEVQNLQVSLKGPADYVSQADRKAEKII
FNELSKARPKFGFLMEESEEIIGEDSQHRFIVDPLDGTTNFLHGIPFFAV
SIALESQGKIVAGVIYNPINDELFTAERGSGAFFNDRRCRVSARRRLEDC
VIATGMPHLPGHGTYLIELRNVMAEVSGIRRFGTAALDLAYVAAGRTDGF
WEDNLQIWDMAAGILMVREAGGFVTDKEGGNDIFRKKNIIAGNEHIRIKL
ERALKKGI

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3lv0 Chain A Residue 264

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3lv0 Crystal structure of extragenic suppressor protein suhB from Bartonella henselae
• Resolution: 1.85 Å
• Binding residue (original residue number in PDB): E69 D86 L88
• Binding residue (residue number reindexed from 1): E66 D83 L85
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E69 D86 L88 D89 T91 D214
• Catalytic site (residue number reindexed from 1): E66 D83 L85 D86 T88 D209
• Enzyme Commision number: 3.1.3.25: inositol-phosphate phosphatase.

Gene Ontology

Molecular Function

• GO:0008934 inositol monophosphate 1-phosphatase activity
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding
• GO:0052832 inositol monophosphate 3-phosphatase activity
• GO:0052833 inositol monophosphate 4-phosphatase activity
• GO:0052834 inositol monophosphate phosphatase activity

Biological Process

• GO:0006020 inositol metabolic process
• GO:0007165 signal transduction
• GO:0046854 phosphatidylinositol phosphate biosynthetic process

External links

• PDB: RCSB:3lv0, PDBe:3lv0, PDBj:3lv0
• PDBsum: 3lv0
• UniProt: A0A0H3M6W8