Structure of PDB 3lun Chain A Binding Site BS01

Receptor Information
>3lun Chain A (length=259) Species: 2214 (Methanosarcina acetivorans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIVKIPVVVHVVWNEEEENISDAQIQSQIDILNKDFRKLNSDVSQVPSVW
SNLIADLGIEFFLATKDPNGNQTTGITRTQTSVTFFTTSDEVKFASSGGE
DAWPADRYLNIWVCHVLKSEIGQDILGYAQFPGGPAETDGVVIVDAAFGT
TGTALPPFDKGRTATHEIGHWLNLYHIWGDELRFEDPCSRSDEVDDTPNQ
ADPNFGCPSYPHVSCSNGPNGDMFMNYCDYVDDKCMVMFTQGQATRVNAC
LDGPRSSFL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3lun Chain A Residue 999 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3lun On the relevance of the Met-turn methionine in metzincins.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H228 H232 H238
Binding residue
(residue number reindexed from 1)		H166 H170 H176
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:3lun, PDBe:3lun, PDBj:3lun
PDBsum3lun
PubMed20202937
UniProtQ8TL28|ULIL_METAC Ulilysin (Gene Name=MA_3214)

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