Structure of PDB 3lsn Chain A Binding Site BS01

Receptor Information

>3lsn Chain A (length=280) Species: 220664 (Pseudomonas protegens Pf-5)

SLTAYQASSQARVDAAMHTLFTAPSPELARLYEAMRYSVMNGGKRVRPLL
AYAACEALGGKPEQANGAACAVELIHAYSLVHDDLPAMDDDDLRRGQPTT
HKAFDEACAILAGDGLQSLAFSALLDPALSDASAEIRLRMVTTLAQAAGP
AGMVGGQAIDLGSVGLKLDQQALEYMHRHKTGALIEASVILGALASGRAE
KGELKALQTYAQAIGLAFQVQDDILDVESDTATLPTYPALLGLAAAKEYA
LELRDQALHALRPFDAAAEPLRELARYIVE

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3lsn Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3lsn Crystal structure of putative geranyltranstransferase from Pseudomonas fluorescens PF-5 complexed with magnesium
• Resolution: 1.35 Å
• Binding residue (original residue number in PDB): D90 D92
• Binding residue (residue number reindexed from 1): D89 D91
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.

Gene Ontology

Molecular Function

• GO:0004337 geranyltranstransferase activity
• GO:0004659 prenyltransferase activity
• GO:0016740 transferase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0008299 isoprenoid biosynthetic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3lsn, PDBe:3lsn, PDBj:3lsn
• PDBsum: 3lsn
• UniProt: Q4K5A6