Structure of PDB 3lqb Chain A Binding Site BS01

Receptor Information
>3lqb Chain A (length=198) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALICEDKSCFWKKNANNIVEVPYVVSGEFSINDKSVIANAISIFHAQTCI
RFVPRSIQADYLSIENKDGCYSAIGRTGGKQVVSLNRKGCVYSGIAQHEL
NHALGFYHEQSRSDRDQYVRINWNNISPGMAYNFLKQKTNNQNTPYDYGS
LMHYGKTAFAIQPGLETITPIPDENVQIGQRQGLSKIDILRINKLYGC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3lqb Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3lqb Crystal structure of zebrafish hatching enzyme 1 from the zebrafish Danio rerio
Resolution1.1 Å
Binding residue
(original residue number in PDB)		H99 H103 H109
Binding residue
(residue number reindexed from 1)		H98 H102 H108
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H99 E100 H103 H109 Y155
Catalytic site (residue number reindexed from 1) H98 E99 H102 H108 Y154
Enzyme Commision number 3.4.24.67: choriolysin H.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3lqb, PDBe:3lqb, PDBj:3lqb
PDBsum3lqb
PubMed20727360
UniProtQ1LW01|HE12_DANRE Hatching enzyme 1.2 (Gene Name=he1.2)

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