Structure of PDB 3l87 Chain A Binding Site BS01

Receptor Information
>3l87 Chain A (length=200) Species: 210007 (Streptococcus mutans UA159) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSAIKTITKASHLIDMNDIIREGHPTLRAVAQDVTFPLNEDDIILGEKML
QFLKNSQDPVTAEKMELRGGVGLAAPQLDISKRIIAVLIPNPEDPPKEAY
ALKEVMYNPRIIAHSVQDAALADGEGCLSVDRVVEGYVIRHSRVTIEYYD
KNSDKKKLKLKGYQSIVVQHEIDHTNGIMFFDRINEKNPFEIKEGLLLIE
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain3l87 Chain A Residue 205 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3l87 The Crystal Structure of smu.143c from Streptococcus mutans UA159
Resolution2.0 Å
Binding residue
(original residue number in PDB)
Q77 A131 H174 H178
Binding residue
(residue number reindexed from 1)
Q77 A127 H170 H174
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G72 Q77 C131 L132 H174 E175 H178
Catalytic site (residue number reindexed from 1) G72 Q77 C127 L128 H170 E171 H174
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

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Molecular Function

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Biological Process
External links
PDB RCSB:3l87, PDBe:3l87, PDBj:3l87
PDBsum3l87
PubMed
UniProtQ8DWC2|DEF_STRMU Peptide deformylase (Gene Name=def)

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