Structure of PDB 3l81 Chain A Binding Site BS01

Receptor Information
>3l81 Chain A (length=250) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEF
SVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRY
QLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHL
PLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPG
PPGLGLGPASLSFELPRHTCSGLQVRFLRLAFPHKWVRHLSHSDAYVIRI
Ligand information
Receptor-Ligand Complex Structure
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PDB3l81 Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		S254 F255 H256 S257 L261 F264 T280 R283
Binding residue
(residue number reindexed from 1)		S70 F71 H72 S73 L77 F80 T96 R99
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3l81, PDBe:3l81, PDBj:3l81
PDBsum3l81
PubMed20230749
UniProtO00189|AP4M1_HUMAN AP-4 complex subunit mu-1 (Gene Name=AP4M1)

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