Structure of PDB 3kxd Chain A Binding Site BS01

Receptor Information
>3kxd Chain A (length=224) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPT
RVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAERYE
NIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMV
EVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAG
DIILGIGKPEEIERLKNYISALVP
Ligand information
Ligand IDCD
InChIInChI=1S/Cd/q+2
InChIKeyWLZRMCYVCSSEQC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Cd++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cd+2]
FormulaCd
NameCADMIUM ION
ChEMBL
DrugBank
ZINC
PDB chain3kxd Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3kxd Structure of the MthK RCK in complex with cadmium.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D184 E210
Binding residue
(residue number reindexed from 1)		D69 E95
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
Biological Process
GO:0006813 potassium ion transport

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Molecular Function
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Biological Process
External links
PDB RCSB:3kxd, PDBe:3kxd, PDBj:3kxd
PDBsum3kxd
PubMed20371380
UniProtO27564|MTHK_METTH Calcium-gated potassium channel MthK (Gene Name=mthK)

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