Structure of PDB 3kqi Chain A Binding Site BS01
Receptor Information
>3kqi Chain A (length=71) Species:
9606
(Homo sapiens) [
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GSMATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIY
HCPNCEKTHGKSTLKKKRTWH
Ligand information
>3kqi Chain B (length=6) Species:
9606
(Homo sapiens) [
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ARTKQT
Receptor-Ligand Complex Structure
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PDB
3kqi
Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
Resolution
1.78 Å
Binding residue
(original residue number in PDB)
Y7 Y14 T17 R18 F19 M20 I21 E22 W29 E39 D46
Binding residue
(residue number reindexed from 1)
Y9 Y16 T19 R20 F21 M22 I23 E24 W31 E41 D48
Enzymatic activity
Enzyme Commision number
1.14.11.-
Gene Ontology
Cellular Component
GO:0048188
Set1C/COMPASS complex
View graph for
Cellular Component
External links
PDB
RCSB:3kqi
,
PDBe:3kqi
,
PDBj:3kqi
PDBsum
3kqi
PubMed
20129925
UniProt
O75151
|PHF2_HUMAN Lysine-specific demethylase PHF2 (Gene Name=PHF2)
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