Structure of PDB 3k62 Chain A Binding Site BS01

Receptor Information
>3k62 Chain A (length=400) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPTWSLDSNGEMRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLTS
YQKFQLFEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQE
KLKNFISSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLIA
ICVDQNANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVVQ
TIIEKLTADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANYI
IQHIVSNDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLEL
LAEMMDEIFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGR
RQTKEGGYDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3k62 Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		K201 F242 N244 Y245 Q248 F285 R288 Q291 H326 K360 Y361 R364 Y413 N415 Y416 Q419 K450 S453 H454 E457 N500 Y501 Q504 S554 K557
Binding residue
(residue number reindexed from 1)		K34 F75 N77 Y78 Q81 F118 R121 Q124 H159 K193 Y194 R197 Y246 N248 Y249 Q252 K283 S286 H287 E290 N333 Y334 Q337 S387 K390
Binding affinityPDBbind-CN: Kd=127nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3k62, PDBe:3k62, PDBj:3k62
PDBsum3k62
PubMed19901328
UniProtQ09312|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)

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