Structure of PDB 3k61 Chain A Binding Site BS01

Receptor Information
>3k61 Chain A (length=393) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPTWSRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLTSYQKFQLF
EQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQEKLKNFIS
SQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLIAICVDQNA
NHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVVQTIIEKLT
ADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANYIIQHIVSN
DDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLELLAEMMDE
IFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGRRQTKEGG
YDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3k61 Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Resolution2.21 Å
Binding residue
(original residue number in PDB)		K201 N244 Y245 K284 R288 Q291 Q322 N323 H326 K360 Y361 R364 Y413 N415 Y416 Q419 K450 S453 H454 E457 N500 Y501 Q504 S554 K557
Binding residue
(residue number reindexed from 1)		K27 N70 Y71 K110 R114 Q117 Q148 N149 H152 K186 Y187 R190 Y239 N241 Y242 Q245 K276 S279 H280 E283 N326 Y327 Q330 S380 K383
Binding affinityPDBbind-CN: Kd=96.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3k61, PDBe:3k61, PDBj:3k61
PDBsum3k61
PubMed19901328
UniProtQ09312|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)

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