Structure of PDB 3k5z Chain A Binding Site BS01

Receptor Information
>3k5z Chain A (length=394) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPTWSLRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLTSYQKFQL
FEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQEKLKNFI
SSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLIAICVDQN
ANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVVQTIIEKL
TADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANYIIQHIVS
NDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLELLAEMMD
EIFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGRRQTKEG
GYDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3k5z Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K201 N244 Y245 R288 Q291 N323 H326 K360 Y361 R364 Y413 N415 Y416 Q419 K450 S453 H454 E457 N500 Y501 Q504 K557
Binding residue
(residue number reindexed from 1)		K28 N71 Y72 R115 Q118 N150 H153 K187 Y188 R191 Y240 N242 Y243 Q246 K277 S280 H281 E284 N327 Y328 Q331 K384
Binding affinityPDBbind-CN: Kd=39.4nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3k5z, PDBe:3k5z, PDBj:3k5z
PDBsum3k5z
PubMed19901328
UniProtQ09312|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)

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