Structure of PDB 3k5q Chain A Binding Site BS01

Receptor Information
>3k5q Chain A (length=400) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPTWSLDSNGEMRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLTS
YQKFQLFEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQE
KLKNFISSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLIA
ICVDQNANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVVQ
TIIEKLTADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANYI
IQHIVSNDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLEL
LAEMMDEIFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGR
RQTKEGGYDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3k5q Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		K201 C204 E208 N244 Y245 R288 Q291 Q322 N323 H326 K360 Y361 R364 Y413 N415 Y416 Q419 K450 S453 H454 E457 N500 Y501 Q504 S554 K557
Binding residue
(residue number reindexed from 1)		K34 C37 E41 N77 Y78 R121 Q124 Q155 N156 H159 K193 Y194 R197 Y246 N248 Y249 Q252 K283 S286 H287 E290 N333 Y334 Q337 S387 K390
Binding affinityPDBbind-CN: Kd=45.8nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3k5q, PDBe:3k5q, PDBj:3k5q
PDBsum3k5q
PubMed19901328
UniProtQ09312|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)

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