Structure of PDB 3k5n Chain A Binding Site BS01

Receptor Information
>3k5n Chain A (length=759) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQV
PRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGG
VTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPL
KWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVAS
RPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGRDN
SELEWFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGWDRMD
EIDRRFAEDKPALATYNLKNCELVTQIFHKTEIMPFLLERATVNGLPVDR
HGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSV
LVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHC
LPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRL
ASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKI
GRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTKRYAGLIQEG
DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLM
AGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQN
RGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFAT
LMTGQLGLF
Ligand information
Receptor-Ligand Complex Structure
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PDB3k5n Structural insight into translesion synthesis by DNA Pol II.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		N698 V699 P701 R755
Binding residue
(residue number reindexed from 1)		N674 V675 P677 R731
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008296 3'-5'-DNA exonuclease activity
Biological Process
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0045004 DNA replication proofreading
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3k5n, PDBe:3k5n, PDBj:3k5n
PDBsum3k5n
PubMed20064374
UniProtP21189|DPO2_ECOLI DNA polymerase II (Gene Name=polB)

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