Structure of PDB 3k4e Chain A Binding Site BS01

Receptor Information
>3k4e Chain A (length=343) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPLLEQLRNSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEVIF
NEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQM
YACRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKAIETIP
IEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDF
IPYLIQDQYGNYVIQYVLQQDQFTNKEMVDIKQEIIETVANNVVEYSKHK
FASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILMIKDQF
ANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLLASVEKLAALVE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3k4e A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q550 R554 Q557 F587 N589 Y590 Y623 R626 Q629 H662 C697 R698 Y731 N733 Y734 Q737 K772 S775 N776 E779 N824 Y825 L864 A865 S866
Binding residue
(residue number reindexed from 1)		Q28 R32 Q35 F65 N67 Y68 Y101 R104 Q107 H140 C175 R176 Y209 N211 Y212 Q215 K250 S253 N254 E257 N302 Y303 L332 A333 S334
Binding affinityPDBbind-CN: Kd=3nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3k4e, PDBe:3k4e, PDBj:3k4e
PDBsum3k4e
PubMed19918084
UniProtQ07807|PUF3_YEAST mRNA-binding protein PUF3 (Gene Name=PUF3)

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