Structure of PDB 3k49 Chain A Binding Site BS01

Receptor Information
>3k49 Chain A (length=353) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPLLEQLRNSSSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEV
IFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSL
QMYACRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKAIET
IPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELK
DFIPYLIQDQYGNYVIQYVLQQDQFTNKEMVDIKQEIIETVANNVVEYSK
HKFASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILMIKD
QFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKSNGNRHLASVEKLAA
LVE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3k49 A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Q550 R554 Q557 F587 N589 Y590 Y623 R626 Q629 Q658 N661 H662 Q665 C697 R698 Q701 N733 Y734 Q737 K772 S775 N776 E779 N824 Y825 L864 A865 S866 K869
Binding residue
(residue number reindexed from 1)		Q30 R34 Q37 F67 N69 Y70 Y103 R106 Q109 Q138 N141 H142 Q145 C177 R178 Q181 N213 Y214 Q217 K252 S255 N256 E259 N304 Y305 L342 A343 S344 K347
Binding affinityPDBbind-CN: Kd=0.31nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3k49, PDBe:3k49, PDBj:3k49
PDBsum3k49
PubMed19918084
UniProtQ07807|PUF3_YEAST mRNA-binding protein PUF3 (Gene Name=PUF3)

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