Structure of PDB 3jzp Chain A Binding Site BS01

Receptor Information
>3jzp Chain A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQH
MVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL
Ligand information
Receptor-Ligand Complex Structure
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PDB3jzp Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
Resolution1.74 Å
Binding residue
(original residue number in PDB)		M53 G57 I60 M61 Y66 Q71 H72 V92 K93 L98 Y99
Binding residue
(residue number reindexed from 1)		M31 G35 I38 M39 Y44 Q49 H50 V70 K71 L76 Y77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3jzp, PDBe:3jzp, PDBj:3jzp
PDBsum3jzp
PubMed19910468
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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