Structure of PDB 3izo Chain A Binding Site BS01

Receptor Information
>3izo Chain A (length=455) Species: 28285 (Human adenovirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPPFVPPRYLRPTGGRNSIRYSELAPLFDTTRVYLVDNKSTDVASLNYQN
DHSNFLTTVIQNNDYSPGEASTQTINLDDRSHWGGDLKTILHTNMPNVNE
FMFTNKFKARVMVSRLPTKDNQVELKYEWVEFTLPEGNYSETMTIDLMNN
AIVEHYLKVGRQNGVLESDIGVKFDTRNFRLGFDPVTGLVMPGVYTNEAF
HPDIILLPGCGVDFTHSRLSNLLGIRKRQPFQEGFRITYDDLEGGNIPAL
LDVDAYQASLKKPVIKPLTEDSKKRSYNLISNDSTFTQYRSWYLAYNYGD
PQTGIRSWTLLCTPDVTCGSEQVYWSLPDMMQDPVTFRSTRQISNFPVVG
AELLPVHSKSFYNDQAVYSQLIRQFTSLTHVFNRFPENQILARPPAPTIT
TVSENVPALTDHGTLPLRNSIGGVQRVTITDARRRTCPYVYKALGIVSPR
VLSSR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3izo Model of the Trimeric Fiber and Its Interactions with the Pentameric Penton Base of Human Adenovirus by Cryo-electron Microscopy.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		V222 M227 P228 Y292 Q293 K376
Binding residue
(residue number reindexed from 1)		V186 M191 P192 Y256 Q257 K262
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075509 endocytosis involved in viral entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3izo, PDBe:3izo, PDBj:3izo
PDBsum3izo
PubMed21146538
UniProtP12538|CAPSP_ADE05 Penton protein (Gene Name=L2)

[Back to BioLiP]