Structure of PDB 3ipq Chain A Binding Site BS01

Receptor Information
>3ipq Chain A (length=220) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLSPEQLGMIEKLVAAQQTPWPEARQQRFAHFTELAIVSVQEIVDFAKQL
PGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNRED
FAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQ
LQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQV
FALRLQDKKLPPLLSEIWDV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ipq X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		V269 K273 R283 E284 I287 A288 K291 P437 L438 E441
Binding residue
(residue number reindexed from 1)		V44 K48 R58 E59 I62 A63 K66 P212 L213 E216
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006629 lipid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3ipq, PDBe:3ipq, PDBj:3ipq
PDBsum3ipq
PubMed20382159
UniProtQ13133|NR1H3_HUMAN Oxysterols receptor LXR-alpha (Gene Name=NR1H3)

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