Structure of PDB 3iay Chain A Binding Site BS01

Receptor Information
>3iay Chain A (length=885) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSFERKKLPTDFDPSLYDISFQQIDAEQSVLNGIKDENTSTVVRFFGVTS
EGHSVLCNVTGFKNYLYVPAPNSSDANDQEQINKFVHYLNETFDHAIDSI
EVVSKQSIWGYSGDTKLPFWKIYVTYPHMVNKLRTAFERGHLSFNSWFSN
GTTTYDNIAYTLRLMVDCGIVGMSWITLPKGKYSMIEPNNRVSSCQLEVS
INYRNLIAHPAEGDWSHTAPLRIMSFDIECAGRIGVFPEPEYDPVIQIAN
VVSIAGAKKPFIRNVFTLNTCSPITGSMIFSHATEEEMLSNWRNFIIKVD
PDVIIGYNTTNFDIPYLLNRAKALKVNDFPYFGRLKTVKQEIKESVFSSK
AYGTRETKNVNIDGRLQLDLLQFIQREYKLRSYTLNAVSAHFLGEQSIIS
DLQNGDSETRRRLAVYCLKDAYLPLRLMEKLMALVNYTEMARVTGVPFSY
LLARGQQIKVVSQLFRKCLEIDTVIPNMQSQASDDQYEGATVIEPIRGYY
DVPIATLDFNSLYPSIMMAHNLCYTTLCNKATVERLNLKIDEDYVITPNG
DYFVTTKRRRGILPIILDELISARKRAKKDLRDEKDPFKRDVLNGRQLAL
KISANSVYGFTGATVGKLPCLAISSSVTAYGRTMILKTKTAVQEKYCIKN
GYKHDAVVVYGDTDSVMVKFGTTDLKEAMDLGTEAAKYVSTLFKHPINLE
FEKAYFPYLLINKKRYAGLFWTNPDKFDKLDQKGLASVRRDSCSLVSIVM
NKVLKKILIERNVDGALAFVRETINDILHNRVDISKLIISKTLAPNYTNP
QPHAVLAERMKRREGVGPNVGDRVDYVIIGGNDKLYNRAEDPLFVLENNI
QVDSRYYLTNQLQNPIISIVAPIIGDKQANGMFVV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3iay Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta
Resolution2.0 Å
Binding residue
(original residue number in PDB)		K444 D762 T763 K814 Y816 K833 G834 R839 R840 D841 T892 Y897 T898 N899 Q901 H903 R923
Binding residue
(residue number reindexed from 1)		K350 D662 T663 K714 Y716 K733 G734 R739 R740 D741 T792 Y797 T798 N799 Q801 H803 R823
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:3iay, PDBe:3iay, PDBj:3iay
PDBsum3iay
PubMed19718023
UniProtP15436|DPOD_YEAST DNA polymerase delta catalytic subunit (Gene Name=POL3)

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