Structure of PDB 3i5y Chain A Binding Site BS01

Receptor Information
>3i5y Chain A (length=509) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTI
KPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVA
PTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPN
IVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGI
LNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPE
AHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTS
FLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGA
RGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPF
VRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSY
RSCIKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPI
GKAMFEIRD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3i5y Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Resolution2.49 Å
Binding residue
(original residue number in PDB)
P188 T189 R190 G220 G221 D223 F224 T242 G244 R245 D248 K252 F277 T382 V383 G408 R415 T433 D434 I531 S532 S536 F576
Binding residue
(residue number reindexed from 1)
P101 T102 R103 G133 G134 D136 F137 T155 G157 R158 D161 K165 F190 T295 V296 G321 R328 T346 D347 I444 S445 S449 F489
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:3i5y, PDBe:3i5y, PDBj:3i5y
PDBsum3i5y
PubMed19748356
UniProtP15424|MS116_YEAST ATP-dependent RNA helicase MSS116, mitochondrial (Gene Name=MSS116)

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