Structure of PDB 3huf Chain A Binding Site BS01
Receptor Information
>3huf Chain A (length=301) Species:
4896
(Schizosaccharomyces pombe) [
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MWIIEAEGDILKGKSRILFPGTYIVGRNVSDDSSHIQVISKSISKRHARF
TILTPSEKDYFTGGPCEFEVKDLDTKFGTKVNEKVVGQNGDSYKEKDLKI
QLGKCPFTINAYWRSMCIQFDNPEMLSQWASNLNLLGIPTGLRDSDATTH
FVMNRQAGSSITVGTMYAFLKKTVIIDDSYLQYLSTVKESVIEDASLMPD
ALECFKNIIKNNDQFPSSPEDCINSLEGFSCAMLNTSSESHHLLELLGLR
ISTFMKELISKTDFVVLNGIFCLTIEQLWKIIIERNSRELISKEIERLKY
A
Ligand information
>3huf Chain E (length=5) Species:
4896
(Schizosaccharomyces pombe) [
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STTDE
Receptor-Ligand Complex Structure
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PDB
3huf
Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Resolution
2.15 Å
Binding residue
(original residue number in PDB)
R27 K41 S42 S44 K45 K76 F77 K104
Binding residue
(residue number reindexed from 1)
R27 K41 S42 S44 K45 K76 F77 K104
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006302
double-strand break repair
GO:0007095
mitotic G2 DNA damage checkpoint signaling
Cellular Component
GO:0030870
Mre11 complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:3huf
,
PDBe:3huf
,
PDBj:3huf
PDBsum
3huf
PubMed
19804755
UniProt
O43070
|NBS1_SCHPO DNA repair and telomere maintenance protein nbs1 (Gene Name=nbs1)
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