Structure of PDB 3hu6 Chain A Binding Site BS01

Receptor Information
>3hu6 Chain A (length=284) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSKLKWCLRVNPKGLDSKD
YLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGF
KKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSQTMNMVKVPECRLADE
LGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKNRVEIND
VEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCS
NLSVENAAEILILADLHSADQLKTQAVDFINYHA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3hu6 Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
R70 Y87 Y123 K129 D130 W131 G132 F133
Binding residue
(residue number reindexed from 1)
R40 Y55 Y90 K96 D97 W98 G99 F100
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3hu6, PDBe:3hu6, PDBj:3hu6
PDBsum3hu6
PubMed19818708
UniProtO43791|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)

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