Structure of PDB 3hn8 Chain A Binding Site BS01

Receptor Information
>3hn8 Chain A (length=279) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD
RKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHD
LIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAG
LLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNP
TYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHG
REHWAEMLANPRKPVEHWHQLVEEKTLSS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3hn8 Chain A Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3hn8 Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		D328 D334 D386 F387 D388
Binding residue
(residue number reindexed from 1)		D34 D40 D92 F93 D94
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3hn8, PDBe:3hn8, PDBj:3hn8
PDBsum3hn8
PubMed20173762
UniProtP40748|SYT3_RAT Synaptotagmin-3 (Gene Name=Syt3)

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