Structure of PDB 3hik Chain A Binding Site BS01
Receptor Information
>3hik Chain A (length=224) Species:
9606
(Homo sapiens) [
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DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDK
YGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPN
SLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSA
IILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEY
GCCKELASRLRYARTMVDKLLSSR
Ligand information
>3hik Chain B (length=5) [
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PLHST
Receptor-Ligand Complex Structure
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PDB
3hik
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
Resolution
1.77 Å
Binding residue
(original residue number in PDB)
W414 D416 Y485 L490 R516 F535 H538 K540
Binding residue
(residue number reindexed from 1)
W44 D46 Y115 L120 R146 F165 H168 K170
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:3hik
,
PDBe:3hik
,
PDBj:3hik
PDBsum
3hik
PubMed
19597481
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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