Structure of PDB 3hh8 Chain A Binding Site BS01

Receptor Information
>3hh8 Chain A (length=280) Species: 301447 (Streptococcus pyogenes serotype M1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDAEKT
SNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEG
ASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAK
LEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEE
EGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFT
DSIAKKGKPGDSYYAMMKWNLDKISEGLAK
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain3hh8 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3hh8 Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes.
Resolution1.87 Å
Binding residue
(original residue number in PDB)
H67 H139 E205 D280
Binding residue
(residue number reindexed from 1)
H38 H110 E176 D251
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0007155 cell adhesion
GO:0030001 metal ion transport
Cellular Component
GO:0005886 plasma membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3hh8, PDBe:3hh8, PDBj:3hh8
PDBsum3hh8
PubMed19463017
UniProtP0A4G4|MTSA_STRP1 Iron ABC transporter substrate-binding lipoprotein MtsA (Gene Name=mtsA)

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