Structure of PDB 3h94 Chain A Binding Site BS01

Receptor Information
>3h94 Chain A (length=297) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPL
TVGDKVQKGTPLLDLTIPDWVEAQSEYLLLRETGGTATQTEGILERLRLA
GMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKI
QGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVD
AATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALIDTGSE
QRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLI
Ligand information
Ligand IDAG
InChIInChI=1S/Ag/q+1
InChIKeyFOIXSVOLVBLSDH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Ag+]
FormulaAg
NameSILVER ION
ChEMBLCHEMBL1230866
DrugBankDB14521
ZINC
PDB chain3h94 Chain A Residue 408 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3h94 Crystal structure of the membrane fusion protein CusB from Escherichia coli
Resolution3.84 Å
Binding residue
(original residue number in PDB)		M324 R368
Binding residue
(residue number reindexed from 1)		M236 R280
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3h94, PDBe:3h94, PDBj:3h94
PDBsum3h94
PubMed19695261
UniProtP77239|CUSB_ECOLI Cation efflux system protein CusB (Gene Name=cusB)

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