Structure of PDB 3h8x Chain A Binding Site BS01

Receptor Information
>3h8x Chain A (length=204) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHIGEHRDDCRELAPGSPIASVSFGASRDFVFRHKDSRG
KSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFR
KILL
Ligand information
Receptor-Ligand Complex Structure
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PDB3h8x Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		V101 F102 H106 P109 R110 F124 S125 H167 I168 G169 H171 C175 Y235
Binding residue
(residue number reindexed from 1)		V47 F48 H52 P55 R56 F70 S71 H113 I114 G115 H117 C121 Y181
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3h8x, PDBe:3h8x, PDBj:3h8x
PDBsum3h8x
PubMed20223766
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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