Structure of PDB 3h7t Chain A Binding Site BS01

Receptor Information
>3h7t Chain A (length=235) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSD
ISIHYGSSYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDK
TTKKIELPSLLYDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRK
SCEEQYKQIEADKYIYDGVFCAGGEYDETYIGYGDAGDPAVQNGTLVGVA
SYISSMPSEFPSVFLRVGYYVLDIKDIISGKVKPQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3h7t Chain A Residue 239 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3h7t Structural mechanisms of inactivation in scabies mite serine protease paralogues.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E178 E209
Binding residue
(residue number reindexed from 1)		E178 E209
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) Q41 N85 Y183 G184 D185 A186
Catalytic site (residue number reindexed from 1) Q41 N85 Y183 G184 D185 A186
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3h7t, PDBe:3h7t, PDBj:3h7t
PDBsum3h7t
PubMed19427318
UniProtQ6VPT2

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