Structure of PDB 3h7b Chain A Binding Site BS01

Receptor Information
>3h7b Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>3h7b Chain C (length=9) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MLWGYLQYV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3h7b T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Resolution1.88 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 Y84 R97 Y99 Y116 T143 K146 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 Y84 R97 Y99 Y116 T143 K146 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3h7b, PDBe:3h7b, PDBj:3h7b
PDBsum3h7b
PubMed20064447
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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