Structure of PDB 3h52 Chain A Binding Site BS01
Receptor Information
>3h52 Chain A (length=247) Species:
9606
(Homo sapiens) [
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HMLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAV
KWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAP
DLIINEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSV
PKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNSQRFYQLTKLLDSM
HEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPGNIKKLLFHQ
Ligand information
>3h52 Chain N (length=15) Species:
9606
(Homo sapiens) [
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NLGLEDIIRKALMGS
Receptor-Ligand Complex Structure
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PDB
3h52
Molecular switch in the glucocorticoid receptor: active and passive antagonist conformations
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
V575 K579 M593 W600
Binding residue
(residue number reindexed from 1)
V50 K54 M68 W75
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3h52
,
PDBe:3h52
,
PDBj:3h52
PDBsum
3h52
PubMed
19913032
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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